This lab is dedicated to the development of in vitro cell
culture models that can be used as systems for toxicity
testing. The goal is to refine, reduce, or replace the use of
animals in traditional toxicology testing protocols by developing
scientifically valid methods that can predict acute, chronic,
local, and systemic toxicity due to drugs and chemicals.
Approved and Funded
NIH, No. 1 R15ES012170-01, P.I.; Title: In Vitro Model
for Gut Absorption and Cytotoxicity, 6/1/03-5/31/2005,
American Foundation for Pharmaceutical
Education (AFPE) Gateway Scholarship
Awarded for the research project: Cellular and Molecular
Toxicity in Human Cells, $5,000.00, 6/1/2002-5/30/2003.
Minority Biomedical Research Support
NIH, No. 5S06GM08153, P.I.; Title: In Vitro Model for
Prediction of Human Toxicity, 3/1/97-5/30/2000, $351,419
International Foundation for Ethical
Graduate Student Fellowship Award, Chicago, IL., P.I.: F.A. Barile,
sponsor for Mr. Anthony Calabro, Ph.D. Candidate, 6/1/06-5/31/09,
Alternatives Research & Development
In Vitro Model for Cytotoxicity Using Mouse Embryonic Stem Cells.
PI: 8/1/07-12/31/08, $40,000;