Associate Professor
Department of Pharmaceutical Sciences
St. Albert Hall, B18B
8000 Utopia Parkway
Queens, NY 11439
(718) 990-5249
gillespm@stjohns.edu
http://www.gillespielab.org
Educational Background
B.A., 1989, University of Vermont, Minor in Zoology
Ph.D., 1998, University of Utah, Oncological Sciences
Teaching
Undergraduate Courses
Human Anatomy & Physiology II
Molecular Pharmacogenomics
Pharmacogenomics Laboratory
Toxicology And Drugs Of Abuse
Human Anatomy & Physiology Laboratory
Public Health
Molecular Toxicology
Graduate Courses
Molecular Toxicology
Current Trends/Research In Teaching Science
Introduction To Biotechnology
Gene Technology Lab
Gene Technology
Research
Areas of Specialization
Protein Biochemistry, Bioinformatics, Proteomics, Genomics,
Immunology, Public Health, and Toxicology
Publications
Gillespie M, Shamovsky V, D’Eustachio P (2010) Human and chicken
TLR pathways: manual curation and computer-based orthology analysis
Mammalian Genome – Submitted Manuscript ID MG-OC-10-0068
Joseph R. Woska, Jr. and Marc E. Gillespie (2010) siRNA-mediated
Identification And Regulation Of The Ternary SNARE Complex
Mediating Mast Cell Degranulation. TAAP, Undergoing Post Revision
Review
Demir, E., Cary, M. P., Paley, S., Fukuda, K., Lemer, C.,
Vastrik, I., Wu, G., D'Eustachio, P., Schaefer, C., Luciano, J.,
Schacherer, F., Martinez-Flores, I., Hu, Z., Jimenez-Jacinto, V.,
Joshi-Tope, G., Kandasamy, K., Lopez-Fuentes, A. C., Mi, H.,
Pichler, E., Rodchenkov, I., Splendiani, A., Tkachev, S., Zucker,
J., Gopinath, G., Rajasimha, H., Ramakrishnan, R., Shah, I., Syed,
M., Anwar, N., Babur, O., Blinov, M., Brauner, E., Corwin, D.,
Donaldson, S., Gibbons, F., Goldberg, R., Hornbeck, P., Luna, A.,
Murray-Rust, P., Neumann, E., Reubenacker, O., Samwald, M., van
Iersel, M., Wimalaratne, S., Allen, K., Braun, B., Whirl-Carrillo,
M., Dahlquist, K., Finney, A., Gillespie, M., Glass, E., Gong, L.,
Haw, R., Honig, M., Hubaut, O., Kane, D., Krupa, S., Kutmon, M.,
Leonard, J., Marks, D., Merberg, D., Petri, V., Pico, A.,
Ravenscroft, D., Ren, L., Shah, N., Sunshine, M., Tang, R., Whaley,
R., Letovksy, S., Buetow, K. H., Rzhetsky, A., Schachter, V.,
Sobral, B. S., Dogrusoz, U., McWeeney, S., Aladjem, M., Birney, E.,
Collado-Vides, J., Goto, S., Hucka, M., Novere, N. L., Maltsev, N.,
Pandey, A., Thomas, P., Wingender, E., Karp, P. D., Sander, C. and
Bader, G. D. (2010)BioPAX - A community standard for pathway data
sharing. Nature Biotechnology. In Press.
Robin A. Haw, Marc Gillespie,Michael A. Caudy (2010)
Knowledge-Based Bioinformatics: From Analysis to Interpretation
Editors: Alterovitz, G., Ramoni, M.; Chapter 12 - Reactome
and Integrative Pathway Knowledge bases, Wiley ISBN:
978-0-470-74831-2
Matthews L, Gopinath G, Gillespie M, Caudy M, Croft D, de Bono
B, Garapati P, Hemish J, Hermjakob H, Jassal B, Kanapin A, Lewis S,
Mahajan S, May B, Schmidt E, Vastrik I, Wu G, Birney E, Stein L,
D'Eustachio P. (2009) Reactome knowledgebase of human biological
pathways and processes. Nucleic Acids Res. 2009 Jan;37(Database
issue):D619-22. Epub 2008 Nov 3.
Vastrik I, D'Eustachio P, Schmidt E, Joshi-Tope G, Gopinath G,
Croft D, de Bono B, Gillespie M, Jassal B, Lewis S, Matthews L, Wu
G, Birney E, Stein L. (2007) Reactome: a knowledgebase of
biological pathways and processes. Genome Biol. 2007 Mar
16;8(3):R39
Gillespie ME: Biomarker discovery and compound evaluation using
two-hybrid proteomic systems. Expert Opinion on Drug Discovery
2006, 1:389-394.
Joshi-Tope G, Gillespie M, Vastrik I, D'Eustachio P, Schmidt E,
de Bono B, Jassal B, Gopinath GR, Wu GR, Matthews L, Lewis S,
Birney E, Stein L. (2005). Reactome: A Knowledgebase of Biological
Pathways. Nucleic Acids Res 1;33(Database issue):D428-32.
Mukherjee, T., Squillante, E., Gillespie, M., and Shao, J.
(2004). Transepithelial electrical resistance is not a reliable
measurement of the Caco-2 monolayer integrity in Transwell. Drug
Deliv 11, 11-18.
Joshi-Tope, G., I. Vastrik, et al. (2003). "The Genome
Knowledgebase: a resource for biologists and bioinformaticists."
Cold Spring Harb Symp Quant Biol 68: 237-43.
Gillespie, M (2003) Affordable proteomics: The two-hybrid
systems. Current Opinion in Molecular Therapeutics 2003
5(3):266-270
Gillespie, M (2003) Two-Hybrid Proteomics: Leveraging
Small-Scale Proteomic Techniques to Take Advantage of Large-Scale
Databases. Preclinica, 2003 May/June 37-41
Carvalho, F. and M. E. Gillespie (2003). "Bringing Proteomics
Into the Lab - Proteomics Lab 101." Biochemistry and Molecular
Biology Education, 2003 31: 46-51.
Presentations
Gillespie, M. E. (2010). Biological Pathway Analysis: An
Introduction to the Pathway Knowledge Bases for Toxicological
Research 49th Annual Society Of Toxicology Meeting, Salt Lake City,
Utah
Gillespie, M. E. (2009).Online Training of New Curators 3rd
International Biocuration Conference Berlin, Germany
Gillespie, M. E. (2009). A Novel Toxicoproteomic/Toxicogenomic
Method For The Identification Of Molecular Biomarkers. Society of
Toxicology Annual Meeting, Baltimore, MD.
Marc Gillespie How would you succinctly describe your
institution’s experience of its Catholic identity to colleagues
outside your institution? A Faculty Perspective 2008 St. John’s
University 2008 Queens, NY
Marc Gillespie, Imre Vastrik, Peter D’Eustachio, Lisa Matthews,
Bijay Jassal, Gopal Gopinath1, Bernard de Bono, Guanming Wu, Esther
Schmidt, Suzanna Lewis, Ewan Birney, and Lincoln D. Stein,
Annotating Infectious Disease Within Reactome, 2006 Baltimore,
MD
Marc Gillespie, Imre Vastrik, Peter D’Eustachio, Lisa Matthews,
Bijay Jassal, Gopal Gopinath1, Bernard de Bono, Guanming Wu, Esther
Schmidt, Suzanna Lewis, Ewan Birney, and Lincoln D. Stein,
Annotating The Mechanisms And Models Of Synaptic Transmission In
Reactome, 2006 Cold Spring Harbor Laboratory, NY
Marc Gillespie, Imre Vastrik, Peter D’Eustachio, Lisa Matthews,
Bijay Jassal, Gopal Gopinath1, Bernard de Bono, Guanming Wu, Esther
Schmidt, Suzanna Lewis, Ewan Birney, and Lincoln D. Stein,
Annotating The Mechanisms And Models Of Cancer In Reactome, 2006
Cold Spring Harbor Laboratory, NY
Marc Gillespie, Imre Vastrik, Peter D’Eustachio, Lisa
Matthews,Geeta Joshi-Tope, Bijay Jassal, Gopal Gopinath1, Bernard
de Bono, Guanming Wu, Esther Schmidt, Suzanna Lewis, Ewan Birney,
and Lincoln D. Stein, Annotating Axon Guidance & Neural
Plasticity Genes In H. Sapiens For The Reactome, Axon Guidance
& Neural Plasticity, 2005 Cold Spring Harbor Laboratory, NY
Marc Gillespie, Imre Vastrik, Peter D’Eustachio, Lisa
Matthews,Geeta Joshi-Tope, Bijay Jassal, Gopal Gopinath1, Bernard
de Bono, Guanming Wu, Esther Schmidt, Suzanna Lewis, Ewan Birney,
and Lincoln D. Stein, Annotating Cancer Genetics & Tumor
Suppressor Genes In H. Sapiens For The Reactome, Cancer Genetics
& Tumor Suppressor Genes, 2005 Cold Spring Harbor Laboratory,
NY
Gillespie, M., Vastrik, I., D’Eustachio, P., Matthews, L.,
Joshi-Tope, G., Jassal, B., Gopinath, G., Bono, B. d., Wu, G.,
Schmidt, E., et al. (2004a). Annotating Axon Guidance & Neural
Plasticity Genes In H. Sapiens For The Reactome. Paper presented
at: Axon Guidance & Neural Plasticity (Cold Spring Harbor
Laboratory, Cold Spring Harbor, NY 11724).
Gillespie, M., Vastrik, I., D’Eustachio, P., Matthews, L.,
Joshi-Tope, G., Jassal, B., Gopinath, G., Bono, B. d., Wu, G.,
Schmidt, E., et al. (2004b). Annotating Cancer Genetics & Tumor
Suppressor Genes In H. Sapiens For The Reactome. Paper presented
at: Cancer Genetics & Tumor Suppressor Genes (Cold Spring
Harbor Laboratory, Cold Spring Harbor, NY 11724).