Recent Publications

Sethia, S. and Squillante, E.  Solid Dispersions: Revival with greater possibilities and applications in oral drug delivery. Critical Reviews in Therapeutic Drug Carrier Systems 20(2&3):217-249 2003.

Rajeswari, R.V., Lau Chem, C., and Squillante, E. “Transdermal permeation of isradipine as liposomes, niosomes and transfersomes through hairless mouse skin.” International Journal of Pharmaceutics September, 2003.

Sethia, S. and Squillante, E.  “Physicochemical characterization of solid dispersions of carbamazepine and PVP K30 formulated by supercritical and conventional solvent evaporation method.” International Journal of Pharmaceutics September, 2003.

Sethia, S. and Squillante, E.  “In Vitro-In Vivo evaluation of supercritical processed solid dispersions: permeability and viability assessment in caco-2 cells.” Pharmaceutical Research, 151, 2003.

Rios, E., Ashby, C. and Squillante, E. “Gamma-vinyl GABA-induced dopamine release following cocaine challenge in the nucleus accumbens.” Current Separations  July 2003.

Rao, R.A., Sethia, S. and Squillante, E. “Crystal habit alteration of a selective COX-2 inhibitor by supercritical carbon dioxide processing.” Submitted to International Journal of Pharmaceutics August 2003 KU-2092.

Rao, R.A., Sethia, S. and Squillante, E. “Preformulation studies of supercritical carbon dioxide-processed solid dispersions of a selective COX-2 inhibitor.”  AAPS Conference on Advance in Pharmaceutical Processing. June 19-20, 2003 Parsipanny, N.J. (awarded “Outstanding Poster” of the meeting)

Bagchi, S. and Squillante, E. “Swelling and permeation studies of Eudragit free films.” Submitted MS#999802 Journal of Pharmacy & Pharmaceutical Sciences April 2003.

Mundhra, D.B., Yoburn, B. Squillante, E.  “Preformulation studies for pH controlled release of ß-galactosidase by Eudragit L100 using supercritical carbon dioxide as the novel method of solvent evaporation.” Submitted to International Journal of Pharmaceutics June 2003 KU-2903.

Sethia, S. and Squillante, E. “Physicochemical characterization of solid dispersions of carbamazepine formulated by supercritical carbon dioxide and conventional solid evaporation method.” Journal of Pharmaceutical Sciences 91:9 (2002) 1948-1957

Squillante, E. and Rios, E. “Measurement of nasal residence time by microdialysis.” Current Separations 19:4 (2002) 127-130.

Squillante, E. and Mehta, K. “Extended release chlorpheniramine maleate from polymethacrylate solid dispersions by supercritical fluid processing" Drug Delivery Technology 2:5 (2002) 58-64.

Alavi, A. K., Mehta, K. and Squillante, E. “Formulation of gastroprotective and enterosoluble microparticles for an acid labile protein.” Journal of Pharmacy and Pharmaceutical Sciences 5:3 (2002) 234-244.

Squillante, E., Morshed, G., Bagchi, S., and Mehta, K. “Microencapsulation of beta-galactosidase with Eudragit L-100.” Journal of Microencapsulation 20:2 (2003) 153-167.

Rajeswari, R.V., Lau Chem, C., and Squillante, E. “In vitro evaluation of the transdermal permeation of isradipine as liposomes, niosomes and transfersomes using hairless mouse skin.” AAPS 2001 Annual Meeting & Exposition, Poster W4258

Alavi, A. K., Squillante, E., Bagchi, S. and Sethia, S. “Evaluation of supercritical carbon dioxide as a substitute for conventional solvents in solvent evaporation process for microencapsulation of acid labile proteins.” AAPS 2001 Annual Meeting & Exposition, October 20, 2001. Poster 2302

Sethia, S. and Squillante, E. “Bioavailability of carbamazepine from self-emulsifying solid dispersions formulated by supercritical fluid technology.”  AAPS 2001 Annual Meeting & Exposition, October 20, 2001. Poster W4190

Morshed, G., Squillante, E., and Bagchi, S. “Microencapsulation of ß-galactosidase with Eüdragit L-100.” AAPS 2001 Annual Meeting & Exposition, October 20, 2001. Poster W4543

Metropolitan American Association for Laboratory Animal Science, Metro AALAS Guest Speaker  “Microdialysis as a Means to Measure CNS Response in Rats.” March 8, 2001 SUNY, Stoneybrook, NY.

Squillante, E., Needham, T. E., Zia, H. "Transdermal Delivery of Calcium Channel Blockers, such as Nifedipine." U.S. Patent # 6,106,856 August 22, 2000.

Challa, R. V., Lau-Cam, C. A., Shahriyar, S. and Squillante, E. “Preparation and characterization of liposomal, niosomal and transfersomal formulations of isradipine.” AAPS: 2000 Annual Meeting & Exposition  November 1, Poster 3382.

Rajeswari, R.V., Lau Chem, C., and Squillante, E. “Comparison of the in vitro permeation of liposomal and nonliposomal formulations of isradipine through hairless mouse skin.”  AAPS: 2000 Annual Meeting & Exposition November 1, Poster 3378

Alavi A.K., Squillante E., and Bagchi S. “The preservative action of polymers on the activity of lactase enzyme treated with supercritical carbon dioxide.” AAPS Annual Meeting, November 14-18, 1999 Poster 2210.

Squillante E. and Neduvelil S. “Preparation of sustained-release powders using supercritical fluid processing technology.” AAPS Annual Meeting, November 14-18, 1999 Poster 3617.

Vemavarapu C., Needham T.E., Squillante E. and Zia H. “Mechanistic evaluation of the treatment of topical hydrofluoric acid burns using a calcium gluconate gel.” AAPS Annual Meeting, November 14-18, 1999 Poster 1005.

Samuel K.B., Chaurasia C.S. and Squillante, E. “Effects of non-steroidal estrogenic agent Tamoxifen on brain cholinergic and dopaminergic systems: an on-line in vivo microdialysis investigation.”  Proceedings of the 8th International Conference on In Vivo Methods: Monitoring Molecules in Neuroscience. June 19-23, 1999 Stony Brook, NY. pages 287-8.

Zia, H., Rashed, S.F., Quadir, M.  Needham, T.E., Squillante, E.  "Ketorolac tromethamine and ketoprofen suppositories release profiles and bioavailability from cocoa butter base formulations in rabbits." International Journal of Pharmaceutical Compounding 2 (1998) 390-393.

Squillante, E., Needham, T. E., Zia, H. “Transdermal delivery of calcium channel blockers.” Eur. Pat. Appl. 0680759A1; Notice for allowances: June 10, 1998.

Squillante, E., Needham, T. E., Zia, H.  “Solubility and in vitro transdermal permeation of nifedipine.”  International Journal of Pharmaceutics 159 171-180 (1997).

Squillante, E., "Evanescent wave optical fiber spectroscopy in drug delivery." Drug Development and Industrial Pharmacy  24 1163-1175 (1998).

Squillante, E., Nanda, A., Needham, T. E., Zia, H. “Optimization of in vitro nifedipine penetration enhancement through hairless mouse skin.”  International Journal of Pharmaceutics 169:2 143?154 (1998).

Squillante, E., Maniar, A., Kislalioglu, S., Needham, T. E., Zia, H. “Codiffusion of propylene glycol and dimethyl isosorbide in hairless mouse skin.” European Journal of Pharmaceutics and Biopharmaceutics 46:3 265-271 (1998).

Squillante, E., Needham, T.E. “Interspecies differences in transdermal delivery of cosolvent permeation enhancers.” Controlled Release Society Annual Meeting Las Vegas, NV 1998 (awarded ten-best poster prize).

Ahmed, A.N., El-Gizawy, S.M., Squillante, E.,  Zia, H., Needham, T.E. “Effect of cyclodextrins and ß-cyclodextrin derivatives on the solubility and skin penetration of nifedipine.” Journal of Pharmaceutical Sciences (submitted).

Dua, R., Duncan, M., Squillante, E., Zia, H., Needham, T.E. “The influence of the enhancer, dimyristoylphosphatidylglycerol and formulation factors on the nasal absorption of salmon calcitonin.”  Drug Delivery March (1997).

Maniar, A., Squillante, E., Kislalioglu, S., Needham, T. E., Zia, H. “Optimization of solution formulations for nifedipine across hairless mouse skin.” Pharmaceutical Development and Technology (submitted MS# PDT 98-012).

Ko, Kuang-Ta, Squillante, E., Needham, T.E., Zia, H., Emulsion formulations of testosterone for nasal administration. J. Microencap., (1998) 15(2), 197-205.

Squillante, E., Needham, T.E., Zia, H. “Solubility parameter as a predictive tool in transdermal design.”  19th Symposium of the Controlled Release Society 495-496, 1992.

Squillante, E. “Innovative Drug Delivery Systems.” Glaxo Wellcome Continuing Education Series.  Rhode Island Society of Hospital Pharmacists, Fall 1996.

“Career Options: Institutional Practice.” College of Pharmacy Centennial Scholars Recognition Day.  University of Rhode Island, 1995.

Squillante, E., Rhodes, C.T., Falk, R.W. “Estimation of Nonlinear Elimination Kinetics: Assessment of Various Methods.” presented at Vicks Research Center, Richardson-Vicks Inc., Shelton, CT 1986.